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Article

Generation of a human embryonic stem cell line WAe009-A-79 carrying a long QT syndrome mutation in KCNQ1.

Stem cell research - 1 Aug 2023

Wang Hongyue, Guo Tianwei, Lan Feng

Abstract excerpt

The voltage-gated potassium channel KvLQT1 encoded by KCNQ1 plays an important role in the repolarization of myocardial action potentials. KCNQ1 mutations can cause Long QT syndrome type 1 (LQT1), which is considered to be the most common causative gene of LQT. In this study, we established a human embryonic stem cell line KCNQ1L114P/+ (WAe009-A-79) carrying a LQT1 related mutation in KCNQ1. The WAe009-A-79 line...

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Identifiers

PMID: 37244124
DOI: 10.1016/j.scr.2023.103119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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Generation of a human embryonic stem cell line WAe009-A-79 carrying a long QT syndrome mutation in KCNQ1.PMID 37244124Read ↗

Establishment of a human induced pluripotent stem cell line, KSCBi015-A, from a long QT syndrome type 1 patient harboring a KCNQ1 mutation.Semantic proximity Read ↗

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Establishment of human embryonic stem cell WAe009-A-48 carrying a long QT syndrome mutation in SCN5A.Semantic proximity Read ↗

Generation of a human embryonic stem cell line (WAe009-A-43) carrying a Long QT syndrome related mutation in KCNH2 gene.Semantic proximity Read ↗

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Establishment of human embryonic stem cell WAe009-A-88 carrying a long QT syndrome mutation in KCNH2.Semantic proximity Read ↗

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Generation and characterization of the human induced pluripotent stem cell (hiPSC) line NCUFi001-A from a patient carrying KCNQ1 G314S mutation.Semantic proximity Read ↗

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