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Article

Establishment of human embryonic stem cell WAe009-A-48 carrying a long QT syndrome mutation in SCN5A.

Stem cell research - 1 Mar 2021

Yang Xiaofei, Wu Fujian, Zhong Jiaqi, Li Furong

Abstract excerpt

The long QT syndrome type 3 (LQT3) is currently the 3rd most prevalent of the 15 known types of LQT syndrome. Cardiac events in LQT3 are less frequent than LQT1 and LQT2, but more likely to be fatal. LQT3 is caused by mutation in gene SCN5A, which codes for the Nav1.5 Na+ channel. Herein, we have generated a human embryonic stem cell line (WAe009-A-48) carrying a LQTS related mutation in SCN5A (WAe009-A-48). The...

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Identifiers

PMID: 33517120
DOI: 10.1016/j.scr.2021.102194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Establishment of human embryonic stem cell WAe009-A-48 carrying a long QT syndrome mutation in SCN5A.PMID 33517120Read ↗

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