Article
Low grade serous ovarian cancer - A rare disease with increasing therapeutic options.
Cancer treatment reviews - 1 Jan 2023
Zwimpfer Tibor A, Tal Ori, Geissler Franziska, Coelho Ricardo, Rimmer Natalie, Jacob Francis, Heinzelmann-Schwarz Viola
Abstract excerpt
High-grade serous ovarian cancers (HGSOCs) most commonly arise from the fimbrial end of the fallopian tube and harbor TP53 gene mutations. In contrast, low-grade serous ovarian cancers (LGSOCs) appear to have different pathological, epidemiological, and clinical features and should be seen as a distinct serous epithelial ovarian cancer subtype. Our current understanding of LGSOC is limited, and treatment has...
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