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Article

Serum levels of glial fibrillary acidic protein in patients with amyotrophic lateral sclerosis.

Annals of clinical and translational neurology - 1 Jan 2023

Verde Federico, Milone Ilaria, Maranzano Alessio, Colombo Eleonora, Torre Silvia, Solca Federica, Doretti Alberto, Gentile Francesco, Manini Arianna, Bonetti Ruggero, Peverelli Silvia, Messina Stefano, Maderna Luca, Morelli Claudia, Poletti Barbara, Ratti Antonia, Silani Vincenzo, Ticozzi Nicola

Abstract excerpt

OBJECTIVE: To compare serum levels of the astrocyte biomarker glial fibrillary acidic protein (GFAP) in patients with amyotrophic lateral sclerosis (ALS) and neurologically healthy controls and to analyze the relations between serum GFAP (sGFAP) and phenotype in ALS. METHODS: We studied 114 ALS patients and 38 controls. sGFAP was quantified with single molecule array (Simoa) technology. RESULTS: In both ALS...

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Identifiers

PMID: 36525477
DOI: 10.1002/acn3.51708
PMCID: PMC9852391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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