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Rapamycin improves the developmental competence of human oocytes by alleviating DNA damage during IVM

1 Jan 2022

Abstract excerpt

Abstract STUDY QUESTION Can rapamycin improve the developmental competence of human oocytes during the IVM process? SUMMARY ANSWER Rapamycin at 10 nM could markedly improve the developmental competence of human oocytes undergoing IVM. WHAT IS KNOWN ALREADY Embryos derived from oocytes that mature in vitro have lower developmental competence than sibling embryos derived from oocytes matured in vivo. Rapamycin was...

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PMID: 36518986
DOI: 10.1093/hropen/hoac050

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