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Article

Time-dependent capability of human oocytes for activation and pronuclear formation during metaphase II arrest

12 Feb 2004

Abstract excerpt

BACKGROUND: The purpose of this study was to investigate the fertilization rate and developmental potential of human oocytes in relation to the duration of their metaphase II (MII) arrest stage following the extrusion of the first polar body (1PB). METHODS: Immature metaphase I oocytes (MI; study oocytes, n = 468) that underwent meiotic maturation during brief in vitro culture and their matured in vivo, MII...

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PMID: 15033953
DOI: 10.1093/humrep/deh158

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