Article
The HLA-Cw*06 allele may predict the response to methotrexate (MTX) treatment in Chinese arthritis-free psoriasis patients.
Archives of dermatological research - 1 Jul 2023
Mao Manyun, Kuang Yehong, Chen Menglin, Yan Kexiang, Lv Chenzhi, Liu Panpan, Lu Yan, Chen Xiang, Zhu Wu, Chen Wangqing
Abstract excerpt
MTX in genetically distinctive Chinese psoriatic patients remains less explored. The present study aimed to determine the impact of HLA-Cw*06 on MTX response in a Chinese psoriasis patient population. A total of 204 patients with psoriasis were enrolled in this study. Clinical data and DNA samples from all patients were collected. The allele of HLA-Cw*06 genotyping was detected using direct Sanger sequencing....
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