Article
HLA polymorphism among Chinese patients with chronic plaque psoriasis: subgroup analysis.
The British journal of dermatology - 1 Feb 2012
Chiu H Y, Huang P-Y, Jee S-H, Hu C-Y, Chou C-T, Chang Y-T, Hwang C-Y, Tsai T-F
Abstract excerpt
BACKGROUND: HLA-Cw*06 has a strong influence on the clinical features and the susceptibility to psoriasis in different ethnicities. It is also used as a biomarker to predict the therapeutic efficacy of biologics, with inconsistent results. Additionally, most Asian patients with psoriasis do not carry HLA-Cw*06. OBJECTIVES: To determine additional HLA alleles which confer susceptibility or affect the severity of...
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