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A stable hepatitis D virus-producing cell line for host target and drug discovery

26 Nov 2022

Abstract excerpt

Chronic hepatitis D is the most aggressive form of chronic viral hepatitis. It is caused by super-infection of hepatitis B virus (HBV)-infected hepatocytes with hepatitis D virus (HDV). While the recent conditional approval of bulevirtide for HDV treatment offers a new therapeutic modality in Europe, there is an unmet medical need to further improve therapy. A more detailed characterization of virus-host...

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PMID: 36511319
DOI: 10.1016/j.antiviral.2022.105477

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