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Article

A review on hepatitis D: From virology to new therapies

29 Mar 2019

Abstract excerpt

Hepatitis delta virus (HDV) is a defective virus that requires the hepatitis B virus (HBV) to complete its life cycle in human hepatocytes. HDV virions contain an envelope incorporating HBV surface antigen protein and a ribonucleoprotein containing the viral circular single-stranded RNA genome associated with both forms of hepatitis delta antigen, the only viral encoded protein. Replication is mediated by the...

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PMID: 31193285
DOI: 10.1016/j.jare.2019.03.009

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