Article
The Role of Calcium, 25-Hydroxyvitamin D, and Parathyroid Hormone in Irritable Bowel Syndrome: A Bidirectional Two-Sample Mendelian Randomization Study.
Nutrients - 1 Dec 2022
Xie Ning, Xie Jiale, Wang Ziwei, Shu Qiuai, Shi Haitao, Wang Jinhai, Liu Na, Xu Feng, Wu Jian
Abstract excerpt
Several observational studies have indicated the potential associations among calcium, vitamin D (Vit-D), and irritable bowel syndrome (IBS). However, the causal relationship deduced from these studies is subject to residual confounding factors and reverse causation. Therefore, we aimed to explore the bidirectional causal effects among serum calcium, Vit-D, PTH, and IBS at the genetic level by a two-sample...
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