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Article

In Vitro Susceptibility of HIV Isolates with High Growth Capability to Antiretroviral Drugs.

International journal of molecular sciences - 6 Dec 2022

Hinay Alfredo A, Kanai Kyosuke, Tsuneki-Tokunaga Akeno, Komatsu Mizuki, Telan Elizabeth O, Kageyama Seiji

Abstract excerpt

It has been considered that reduced susceptibility to antiretroviral drugs is influenced by drug adherence, drug tolerance and drug-resistance-related mutations in the HIV genome. In the present study, we assessed the intrinsic high viral growth capability as a potential viral factor that may influence their susceptibility to antiretroviral drugs using an in vitro model. Phytohemagglutinin-activated peripheral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36499705
DOI: 10.3390/ijms232315380
PMCID: PMC9737537

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