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Article

Impact of Four Ovine TMEM154 Haplotypes on Ewes during Multiyear Lentivirus Exposure.

International journal of molecular sciences - 29 Nov 2022

Freking Brad A, Murphy Tom W, Chitko-McKown Carol G, Workman Aspen M, Heaton Michael P

Abstract excerpt

Polypeptide variation encoded by the ovine transmembrane protein 154 gene (TMEM154) is associated with susceptibility to ovine lentivirus, the causative agent of Ovine Progressive Pneumonia (OPP) and Visna/Maedi. Our aim was to compare the four most prevalent TMEM154 haplotypes on the incidence of infection and ewe productivity during natural multiyear virus exposure. Prospective cohort studies were designed to...

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Identifiers

PMID: 36499292
DOI: 10.3390/ijms232314966
PMCID: PMC9741230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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