Article
Small ruminant lentivirus genetic subgroups associate with sheep TMEM154 genotypes.
Veterinary research - 29 Jul 2013
Sider Lucia H, Heaton Michael P, Chitko-McKown Carol G, Harhay Greg P, Smith Timothy P L, Leymaster Kreg A, Laegreid William W, Clawson Michael L
Abstract excerpt
Small ruminant lentiviruses (SRLVs) are prevalent in North American sheep and a major cause of production losses for the U.S. sheep industry. Sheep susceptibility to SRLV infection is influenced by genetic variation within the ovine transmembrane 154 gene (TMEM154). Animals with either of two distinct TMEM154 haplotypes that both encode glutamate at position 35 of the protein (E35) are at greater risk of SRLV...
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