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Article

Genetic testing for TMEM154 mutations associated with lentivirus susceptibility in sheep.

PloS one - 1 Jan 2013

Heaton Michael P, Kalbfleisch Theodore S, Petrik Dustin T, Simpson Barry, Kijas James W, Clawson Michael L, Chitko-McKown Carol G, Harhay Gregory P, Leymaster Kreg A

Abstract excerpt

In sheep, small ruminant lentiviruses cause an incurable, progressive, lymphoproliferative disease that affects millions of animals worldwide. Known as ovine progressive pneumonia virus (OPPV) in the U.S., and Visna/Maedi virus (VMV) elsewhere, these viruses reduce an animal's health, productivity, and lifespan. Genetic variation in the ovine transmembrane protein 154 gene (TMEM154) has been previously associated...

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Identifiers

PMID: 23408992
DOI: 10.1371/journal.pone.0055490
PMCID: PMC3569457

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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