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Synapsin III Regulates Dopaminergic Neuron Development in Vertebrates

2 Dec 2022

Abstract excerpt

Attention deficit and hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by alterations in the mesocorticolimbic and nigrostriatal dopaminergic pathways. Polymorphisms in the Synapsin III (Syn III) gene can associate with ADHD onset and even affect the therapeutic response to the gold standard ADHD medication, methylphenidate (MPH), a monoamine transporter inhibitor whose efficacy...

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PMID: 36497160
DOI: 10.3390/cells11233902

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