Article
Kidney cancer pathology in the new context of targeted therapy.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2011
Allory Yves, Culine Stéphane, de la Taille Alexandre
Abstract excerpt
The outcome in metastatic renal cancer remains poor with an overall survival at 5 years of less than 10%. However, molecular pathology in kidney cancer has developed extensively in the few last years, providing a basis for new systemic therapies including antiangiogenic drugs and mTOR inhibitors. Use of these targeted therapies in metastatic disease has improved the prognosis but still in a too-limited range,...
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