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Generation of a human iPSC line (CIBi013-A) from a patient with young-onset Parkinson's disease carrying a novel homozygous PARK7 (DJ-1) mutation.

Stem cell research - 1 Feb 2023

Li Lingfei, Si Xiaoli, Lei Meng, Yang Jiayin, Ruan Jie, Liu Huifang, Huang Feifan, Jin Xuanxiang, Xie Keyue, Yang Hui, Lei Xiaoguang, Liu Yao

Abstract excerpt

Mutations in PARK7 and the resulting alterations in its production protein (DJ-1) are tightly associated with Parkinson's disease. We generated a human induced pluripotent stem cell (iPSC) line (CIBi013-A) from a patient with young-onset Parkinson's disease (YOPD) who carried a novel homozygous PARK7 (DJ-1) mutation (chr1:8037723, c.334C>G). The generated iPSCs will be used for investigating phenotype and...

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PMID: 36469984
DOI: 10.1016/j.scr.2022.102983

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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