Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Longitudinal Analysis of the Microbiome and Metabolome in the 5xfAD Mouse Model of Alzheimer’s Disease

5 Dec 2022

Abstract excerpt

Microorganisms residing within the gastrointestinal tract are implicated in the onset and progression of Alzheimer's disease (AD) through the mediation of inflammation, exchange of small-molecules across the blood-brain barrier, and stimulation of the vagus nerve. Unfortunately, most animal models for AD are housed under conditions that do not reflect real-world human microbial exposure and do not sufficiently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biochemical effects in animals
Share to Gut microbiota and health
Share to Tryptophan and brain disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36468884
DOI: 10.1128/mbio.01794-22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Longitudinal Analysis of the Microbiome and Metabolome in the 5xfAD Mouse Model of Alzheimer’s DiseasePMID 36468884Read ↗

Longitudinal and Multi-Kingdom Gut Microbiome Alterations in a Mouse Model of Alzheimer’s DiseaseSemantic proximity Read ↗

Impact of Acute and Chronic Amyloid-β Peptide Exposure on Gut Microbial Commensals in the MouseSemantic proximity Read ↗

Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer’s Mouse ModelSemantic proximity Read ↗

Sex-Specific Gut Microbiome Functions in Alzheimer’s Disease BXD MiceSemantic proximity Read ↗

The impact of APOE genotype, age, and sex on gut microbiota in a mouse model of Alzheimer's Disease: an exploration of their interactions.Semantic proximity Read ↗

Bridging the Gap between Gut Microbiota and Alzheimer’s Disease: A Metaproteomic Approach for Biomarker Discovery in Transgenic MiceSemantic proximity Read ↗

Sex-specific associations between AD genotype and the microbiome of human amyloid beta knock-in (hAβ-KI) mice.Semantic proximity Read ↗

Ketogenic interventions prevent alterations of the gut microbiome in transgenic Alzheimer’s Disease miceSemantic proximity Read ↗

The link between gut microbiome and Alzheimer's disease: From the perspective of new revised criteria for diagnosis and staging of Alzheimer's diseaseSemantic proximity Read ↗

Gut Microbiome rewiring via fecal transplants: Uncovering therapeutic avenues in Alzheimer’s disease modelsSemantic proximity Read ↗

A Multi-Organ Murine Metabolomics Atlas Reveals Molecular Dysregulations in Alzheimer’s DiseaseSemantic proximity Read ↗

Gut microbiota dysbiosis in Alzheimer's disease (AD): Insights from human clinical studies and the mouse AD modelsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.