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Exploring new antiviral targets for influenza and COVID-19: Mapping promising hot spots in viral RNA polymerases

18 Nov 2022

Abstract excerpt

Influenza and COVID-19 are infectious respiratory diseases that represent a major concern to public health with social and economic impact worldwide, for which the available therapeutic options are not satisfactory. The RdRp has a central role in viral replication and thus represents a major target for the development of antiviral approaches. In this study, we focused on Influenza A virus PB1 polymerase protein...

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PMID: 36463618
DOI: 10.1016/j.virol.2022.11.001

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