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Structural Homology-Based Drug Repurposing Approach for Targeting NSP12 SARS-CoV-2

10 Nov 2022

Abstract excerpt

The severe acute respiratory syndrome coronavirus 2, also known as SARS-CoV-2, is the causative agent of the COVID-19 global pandemic. SARS-CoV-2 has a highly conserved non-structural protein 12 (NSP-12) involved in RNA-dependent RNA polymerase (RdRp) activity. For the identification of potential inhibitors for NSP-12, computational approaches such as the identification of homologous proteins that have been...

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PMID: 36431833
DOI: 10.3390/molecules27227732

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