Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An update on inhibitors targeting RNA-dependent RNA polymerase for COVID-19 treatment: Promises and challenges

6 Oct 2022

Abstract excerpt

The highly transmissible variants of SARS-CoV-2, the causative pathogen of the COVID-19 pandemic, bring new waves of infection worldwide. Identification of effective therapeutic drugs to combat the COVID-19 pandemic is an urgent global need. RNA-dependent RNA polymerase (RdRp), an essential enzyme for viral RNA replication, is the most promising target for antiviral drug research since it has no counterpart in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA and protein synthesis mechanisms
Share to SARS-CoV-2 and COVID-19 Research
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36209840
DOI: 10.1016/j.bcp.2022.115279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An update on inhibitors targeting RNA-dependent RNA polymerase for COVID-19 treatment: Promises and challengesPMID 36209840Read ↗

RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug DiscoverySemantic proximity Read ↗

SARS-CoV-2 RNA-dependent RNA polymerase as a therapeutic target for COVID-19Semantic proximity Read ↗

Recent advances in the discovery of potent RNA-dependent RNA-polymerase (RdRp) inhibitors targeting virusesSemantic proximity Read ↗

RNA‐dependent RNA polymerase of SARS‐CoV‐2 as a therapeutic targetSemantic proximity Read ↗

Recent advancements in the discovery of small-molecule non-nucleoside inhibitors targeting SARS-CoV-2 RdRpSemantic proximity Read ↗

Insights into RNA-dependent RNA Polymerase Inhibitors as Antiinfluenza Virus AgentsSemantic proximity Read ↗

RdRp inhibitors and COVID-19: Is molnupiravir a good option?Semantic proximity Read ↗

Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 DrugsSemantic proximity Read ↗

Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 DrugsSemantic proximity Read ↗

Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design ChallengeSemantic proximity Read ↗

Inhibition of Viral RNA-Dependent RNA Polymerases by Nucleoside Inhibitors: An Illustration of the Unity and Diversity of MechanismsSemantic proximity Read ↗

RNA-dependent RNA polymerase: Structure, mechanism, and drug discovery for COVID-19Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.