Article
The SARS-CoV-2 replication-transcription complex is a priority target for broad-spectrum pan-coronavirus drugs
2021-03-23
Abstract excerpt
<h4>ABSTRACT</h4> In the absence of effective treatment, COVID-19 is likely to remain a global disease burden. Compounding this threat is the near certainty that novel coronaviruses with pandemic potential will emerge in years to come. Pan-coronavirus drugs – agents active against both SARS-CoV-2 and other coronaviruses – would address both threats. A strategy to develop such broad-spectrum inhibitors is to pharm...
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Identifiers and source
- Literature Corpus work
- d3bfec31-5ad3-5545-8f18-798c92e844b2
- DOI
- 10.1101/2021.03.23.436637
