Article
From high masked to high realized genetic load in inbred Scandinavian wolves.
Molecular ecology - 1 Apr 2023
Smeds Linnéa, Ellegren Hans
Abstract excerpt
When new mutations arise at functional sites they are more likely to impair than improve fitness. If not removed by purifying selection, such deleterious mutations will generate a genetic load that can have negative fitness effects in small populations and increase the risk of extinction. This is relevant for the highly inbred Scandinavian wolf (Canis lupus) population, founded by only three wolves in the 1980s...
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