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Article

Whole-genome resequencing of temporally stratified samples reveals substantial loss of haplotype diversity in the highly inbred Scandinavian wolf population.

Genome research - 1 Mar 2022

Viluma Agnese, Flagstad Øystein, Åkesson Mikael, Wikenros Camilla, Sand Håkan, Wabakken Petter, Ellegren Hans

Abstract excerpt

Genetic drift can dramatically change allele frequencies in small populations and lead to reduced levels of genetic diversity, including loss of segregating variants. However, there is a shortage of quantitative studies of how genetic diversity changes over time in natural populations, especially on genome-wide scales. Here, we analyzed whole-genome sequences from 76 wolves of a highly inbred Scandinavian...

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PMID: 35135873
DOI: 10.1101/gr.276070.121
PMCID: PMC8896455

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