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Article

Strongly deleterious mutations influence reproductive output and longevity in an endangered population.

Nature communications - 27 Sept 2024

Hasselgren Malin, Dussex Nicolas, von Seth Johanna, Angerbjörn Anders, Dalén Love, Norén Karin

Abstract excerpt

Inbreeding depression has been documented in various fitness traits in a wide range of species and taxa, however, the mutational basis is not yet well understood. We investigate how putatively deleterious variation influences fitness and is shaped by individual ancestry by re-sequencing complete genomes of 37 individuals in a natural arctic fox (Vulpes lagopus) population subjected to both inbreeding depression...

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Identifiers

PMID: 39333094
DOI: 10.1038/s41467-024-52741-4
PMCID: PMC11436772

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