Article
Testing Association of Previously Implicated Gene Sets and Gene-Networks in Nicotine Exposed Mouse Models with Human Smoking Phenotypes.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 6 Apr 2023
Mize Travis J, Funkhouser Scott A, Buck Jordan M, Stitzel Jerry A, Ehringer Marissa A, Evans Luke M
Abstract excerpt
INTRODUCTION: Smoking behaviors are partly heritable, yet the genetic and environmental mechanisms underlying smoking phenotypes are not fully understood. Developmental nicotine exposure (DNE) is a significant risk factor for smoking and leads to gene expression changes in mouse models; however, it is unknown whether the same genes whose expression is impacted by DNE are also those underlying smoking genetic...
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