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Article

The role of PRDM1 gene polymorphism in the progression of hepatocellular carcinoma in Egyptian patients.

Journal of medical virology - 1 Jan 2023

Mohamed Amal Ahmed, Esmail Omnia Ezzat, Ibrahim Aya Mohamed Ahmed, Makled Sahar, Al-Hussain Eman, Elsaid Ali, Alboraie Mohamed, El-Awady Rehab R

Abstract excerpt

In Egypt, hepatocellular carcinoma (HCC) ranks as the second largest cause of cancer mortality. PRDM1 is a tumor suppressor gene essential for the differentiation and regulation activity of plasma cells and T cells. It plays a vital role in T cell exhaustion of chronic viral infection and HCC. We aimed to study the role of PRDM1 gene polymorphism in HCV and HCC-related to hepatitis C virus (HCV) progress in...

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Identifiers

PMID: 36424348
DOI: 10.1002/jmv.28343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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