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Impact on Macrolide Resistance of Genetic Diversity of Mycobacterium abscessus Species

23 Nov 2022

Abstract excerpt

Macrolides are the mainstays of the antimycobacterial regimens against Mycobacterium abscessus species (formerly Mycobacterium abscessus complex). erm (41) confers inducible macrolide resistance for M. abscessus subsp. bolletii strains, and the majority of M. abscessus subsp. abscessus T28 sequevars. Furthermore, the acquired macrolide resistance of M. abscessus species is due to a point mutation in rrl .

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PMID: 36416559
DOI: 10.1128/spectrum.02749-22

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