Article
Genetic correlates of clarithromycin susceptibility among isolates of the Mycobacterium abscessus group and the potential clinical applicability of a PCR-based analysis of erm(41).
The Journal of antimicrobial chemotherapy - 1 Apr 2018
Carvalho Natalia F G de, Pavan Fernando, Sato Daisy N, Leite Clarice Q F, Arbeit Robert D, Chimara Erica
Abstract excerpt
Objectives: To define the genetic basis of clarithromycin resistance among isolates of the Mycobacterium abscessus group (MAG). Methods: We analysed 133 isolates identified as MAG. Species identification was confirmed by sequencing the rpoB gene. Clarithromycin susceptibility testing was performed according to CLSI recommendations, with an extended 14 day incubation. Known resistance genotypes of erm(41) and rrl...
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