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Article

Cytoskeletal transgelin 2 contributes to gender‐dependent adipose tissue expandability and immune function

30 May 2019

Abstract excerpt

ABSTRACT During adipogenesis, preadipocytes' cytoskeleton reorganizes in parallel with lipid accumulation. Failure to do so may impact the ability of adipose tissue (AT) to shift between lipid storage and mobilization. Here, we identify cytoskeletal transgelin 2 (TAGLN2) as a protein expressed in AT and associated with obesity and inflammation, being normalized upon weight loss. TAGLN2 was primarily found in the...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 31145872
DOI: 10.1096/fj.201900479r

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