Article
Identification of prognostic parameters in CLL with no abnormalities detected by chromosome banding and FISH analyses.
British journal of haematology - 1 Oct 2018
Vetro Calogero, Haferlach Torsten, Jeromin Sabine, Stengel Anna, Zenger Melanie, Nadarajah Niroshan, Baer Constance, Weissmann Sandra, Kern Wolfgang, Meggendorfer Manja, Haferlach Claudia
Abstract excerpt
Chronic Lymphocytic Leukaemia (CLL) is a heterogeneous disease with a clinical course dependent on cytogenetic features. However, in 15-20% of cases both chromosome banding and fluorescence in situ hybridisation analyses do not show any kind of abnormality. With the aim to identify dependable molecular prognostic factors in this subgroup, we performed a comprehensive analysis on 171 patients including genomic...
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