Article

Ovarian embryonal rhabdomyosarcoma is a rare manifestation of the DICER1 syndrome

2014-11-10

Abstract excerpt

Embryonal rhabdomyosarcoma (ERMS), a malignant soft tissue sarcoma, is one of the most common paediatric cancers. Certain ERMS tumours are associated with the DICER1 syndrome, a distinctive tumour predisposition syndrome caused by germ-line mutations in the microRNA-maturation pathway gene, DICER1 . In addition to germ-line DICER1 mutations, highly characteristic somatic mutations have been identified in several...

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Literature Corpus work: 87b47c2f-c715-596e-a723-ee01bf1897f8
DOI: 10.1101/011304

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