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Changing practice: red blood cell typing by molecular methods for patients with sickle cell disease

9 Jan 2015

Abstract excerpt

BACKGROUND: Extended red blood cell (RBC) antigen matching is recommended to limit alloimmunization in patients with sickle cell disease (SCD). DNA-based testing to predict blood group phenotypes has enhanced availability of antigen-negative donor units and improved typing of transfused patients, but replacement of routine serologic typing for non-ABO antigens with molecular typing for patients has not been...

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PMID: 25573464
DOI: 10.1111/trf.12987

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