Article
Application of genomics for transfusion therapy in sickle cell anemia.
Blood cells, molecules & diseases - 1 Sept 2017
Chou Stella T, Westhoff Connie M
Abstract excerpt
The application of genomic approaches is impacting all areas of laboratory testing including transfusion medicine. Use of DNA-based test methods is particularly applicable for red cell and platelet antigen typing as the majority of genes encoding the carrier proteins and carbohydrates are now known and were cloned in the 1990's. Many of the antigenic polymorphisms are due to single nucleotide changes (SNP's) in...
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