Article
Cytopathological assessment is an accurate method for identifying immunophenotypic features and BRCA1/2 mutations of high-grade serous carcinoma from ascites.
Cancer cytopathology - 1 Mar 2023
Miceska Simona, Škof Erik, Novaković Srdjan, Stegel Vida, Jeričević Anja, Grčar Kuzmanov Biljana, Smrkolj Špela, Cvjetičanin Branko, Bebar Sonja, Globočnik Kukovica Marta, Kloboves-Prevodnik Veronika
Abstract excerpt
BACKGROUND: High-grade serous carcinoma (HGSC) is the most common and aggressive type of ovarian cancer, and it is often associated with ascites at presentation. The objective of this study was to evaluate the accuracy of cytopathology to identify immunophenotypic features of HGSC and BRCA1/2 mutations from ascites. METHODS: The study included 45 patients with histologically confirmed primary HGSC and malignant...
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