Article
Interobserver Reproducibility in Assessing Eosinophilic Cells in Ovarian Serous Borderline Tumors to Predict BRAF Mutational Status.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Sept 2023
Chui M Herman, Murali Rajmohan, Soslow Robert A, Matrai Cathleen, Xing Deyin, Vang Russell
Abstract excerpt
Ovarian serous borderline tumors (SBTs) harboring the BRAFV600E mutation are associated with decreased risk of progression to low-grade serous carcinoma, and often prominently feature tumor cells with abundant eosinophilic cytoplasm. Since eosinophilic cells (ECs) may be a marker of the underlying genetic driver, we proposed morphologic criteria and evaluated the interobserver reproducibility for assessing this...
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