Article
Allograft recognition by recipient's natural killer cells: Molecular mechanisms and role in transplant rejection.
HLA - 1 Sept 2021
Hamada Sarah, Dubois Valérie, Koenig Alice, Thaunat Olivier
Abstract excerpt
The current transplant immunology dogma defends that allograft rejection is initiated by recipient's adaptive immune system. In this prevalent model, innate immune cells in general, and natural killer (NK) cells in particular, are merely considered as downstream effectors which participate in the destruction of the graft only upon recruitment by adaptive effectors: alloreactive T cells or donor-specific...
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