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Human inborn errors of immunity: An expanding universe

3 Jul 2020

Abstract excerpt

Molecular, cellular, and clinical studies of human inborn errors of immunity have revolutionized our understanding of their pathogenesis, considerably broadened their spectrum of immunological and clinical phenotypes, and enabled successful targeted therapeutic interventions. These studies have also been of great scientific merit, challenging a number of immunological notions initially established in inbred mice...

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PMID: 32651211
DOI: 10.1126/sciimmunol.abb1662

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