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Article

Dysregulation of epigenetic modifications in inborn errors of immunity.

Epigenomics - 1 Jan 2024

Xiao Zhongyao, He Rongjing, Zhao Zihan, Chen Taiping, Ying Zhengzhou

Abstract excerpt

Inborn errors of immunity (IEIs) are a group of typically monogenic disorders characterized by dysfunction in the immune system. Individuals with these disorders experience increased susceptibility to infections, autoimmunity and malignancies due to abnormal immune responses. Epigenetic modifications, including DNA methylation, histone modifications and chromatin remodeling, have been well explored in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39404224
DOI: 10.1080/17501911.2024.2410695
PMCID: PMC11534118

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