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Article

What can clinical immunology learn from inborn errors of epigenetic regulators?

The Journal of allergy and clinical immunology - 1 May 2021

Camacho-Ordonez Nadezhda, Ballestar Esteban, Timmers H Th Marc, Grimbacher Bodo

Abstract excerpt

The epigenome is at the interface between environmental factors and the genome, regulating gene transcription, DNA repair, and replication. Epigenetic modifications play a crucial role in establishing and maintaining cell identity and are especially crucial for neurology, musculoskeletal integrity, and the function of the immune system. Mutations in genes encoding for the components of the epigenetic machinery...

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Identifiers

PMID: 33609625
DOI: 10.1016/j.jaci.2021.01.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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