Article
Molecular and serological analysis of the D variant in the Chinese population and identification of seven novel RHD alleles.
Transfusion - 1 Feb 2023
Wen Jizhi, Jia Shuangshuang, Wang Zhen, Chen Jingwang, Liang Qianni, Wei Ling, Richard Gaëlle, Fichou Yann, Luo Guangping, Ji Yanli
Abstract excerpt
BACKGROUND: The molecular basis of the D variant phenotype in the Chinese differs greatly from that of the Caucasian. Adapting a specific D typing strategy to the spectrum of prevalent RHD variant alleles is necessary. STUDY DESIGN AND METHODS: Blood samples with ambiguous D phenotypes were collected in the Southern Chinese population. A special three-step typing strategy was applied. First, the common DVI type 3...
Topics
- Pregnancy
- Female
- Humans
- Alleles
- East Asian People
- Genotype
- Phenotype
- Epitopes
- Rh-Hr Blood-Group System