Article
Molecular bases of unexpressed RHD alleles in Chinese D- persons.
Transfusion - 1 Aug 2009
Ye Luyi, Yue Danqi, Wo Dele, Ding Xiyu, Guo Shuangmei, Li Qin, Guo Zhonghui, Zhu Ziyan
Abstract excerpt
BACKGROUND: The aim of this study was to use a systematic survey to analyze RHD alleles in Chinese D- donors who do not express D antigen or who lack functional RhD protein. STUDY DESIGN AND METHODS: A total of 733 D-Chinese donors, not including Del phenotypes, were investigated by RHD polymorphism–specific polymerase chain reaction (PCR), Rhesus box PCR-PstI digestion, and RHD sequencing. The frequencies of...
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