Article
Molecular background of Rh D-positive, D-negative, D(el) and weak D phenotypes in Chinese.
Vox sanguinis - 1 Aug 2002
Shao C-P, Maas J-H, Su Y-Q, Köhler M, Legler T J
Abstract excerpt
BACKGROUND AND OBJECTIVES: The aim of this study was to elucidate the genetic background of D-negative and D(el) in the Chinese population. MATERIALS AND METHODS: We investigated nine D-positive, 76 D-negative, 26 D(el) and three weak D Chinese individuals by amplification and sequencing of the complete coding region of the RHD gene from genomic DNA. A new RHD polymerase chain reaction with sequence-specific...
Topics
- Alleles
- Asian People
- China
- DNA Primers
- Gene Frequency
- Genotype
- Humans
- Phenotype
- Polymerase Chain Reaction
- Rh-Hr Blood-Group System
- Sensitivity and Specificity