Article
Telomeres, NAFLD and Chronic Liver Disease.
International journal of molecular sciences - 15 Mar 2016
Donati Benedetta, Valenti Luca
Abstract excerpt
Telomeres consist of repeat DNA sequences located at the terminal portion of chromosomes that shorten during mitosis, protecting the tips of chromosomes. During chronic degenerative conditions associated with high cell replication rate, progressive telomere attrition is accentuated, favoring senescence and genomic instability. Several lines of evidence suggest that this process is involved in liver disease...
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