Article
Mouse models of Kras activation in gastric cancer.
Experimental & molecular medicine - 1 Nov 2022
Won Yoonkyung, Choi Eunyoung
Abstract excerpt
Gastric cancer has one of the highest incidence rates and is one of the leading causes of cancer-related mortality worldwide. Sequential steps within the carcinogenic process are observed in gastric cancer as well as in pancreatic cancer and colorectal cancer. Kirsten rat sarcoma viral oncogene homolog (KRAS) is the most well-known oncogene and can be constitutively activated by somatic mutations in the gene...
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