Article
Transgenic and gene knockout mice in gastric cancer research.
Oncotarget - 10 Jan 2017
Jiang Yannan, Yu Yingyan
Abstract excerpt
Mouse models are useful tool for carcinogenic study. They will greatly enrich the understanding of pathogenesis and molecular mechanisms for gastric cancer. However, only few of mice could develop gastric cancer spontaneously. With the development and improvement of gene transfer technology, investigators created a variety of transgenic and knockout/knockin mouse models of gastric cancer, such as INS-GAS mice and...
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