Article
Recapitulating Human Gastric Cancer Pathogenesis: Experimental Models of Gastric Cancer.
Advances in experimental medicine and biology - 1 Jan 2016
Ding Lin, El Zaatari Mohamad, Merchant Juanita L
Abstract excerpt
This review focuses on the various experimental models to study gastric cancer pathogenesis, with the role of genetically engineered mouse models (GEMMs) used as the major examples. We review differences in human stomach anatomy compared to the stomachs of the experimental models, including the mouse and invertebrate models such as Drosophila and C. elegans. The contribution of major signaling pathways, e.g.,...
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