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The regulation of host cellular and gut microbial metabolism in the development and prevention of colorectal cancer

23 Jan 2018

Abstract excerpt

Metabolism regulation is crucial in colorectal cancer (CRC) and has emerged as a remarkable field currently. The cellular metabolism of glucose, amino acids and lipids in CRC are all reprogrammed. Each of them changes tumour microenvironment, modulates bacterial composition and activity, and eventually promotes CRC development. Metabolites such as short chain fatty acids, secondary bile acids, N-nitroso...

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PMID: 29359994
DOI: 10.1080/1040841x.2018.1425671

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