Article

Serum Short-Chain Fatty Acids in Colorectal Cancer: Diagnostic Performance and Decoupling from Gut Producer Abundance

2026-05-28

Abstract excerpt

Gut microbiota–derived short-chain fatty acids (SCFAs) shape epithelial and immune homeostasis, yet systemic SCFA profiles may diverge from gut microbial composition due to absorption and host metabolism. We quantified fasting serum SCFAs in 36 surgically resected Colorectal Cancer (CRC) patients and 20 cancer-free controls using targeted high performance liquid chromatography-triple quadrupole mass spectrometry,...

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Literature Corpus work: 4925384d-49c1-5f28-a62c-cd4cc5ce4370
DOI: 10.20944/preprints202605.1794.v1

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